One of my co-workers has all syntax coloring disabled because of a visual thing where colors cause text to appear to pop off the page and float around.

I nearly have it disabled - mine is all muted grays, with keywords especially visually ducked so my own stuff stands out. I got tired of the "rainbow word salad" effect a few years ago and settled on a much more muted appearance after that.

I also have Xcode set up to use a proportional width font, but that's probably a bridge too far for most people. ;)

(And doesn't work in terminals, because they expect to treat the screen as a character matrix.)